Preliminary programme

October 10th

19.00-20.00 Arrival and Registration

October 11th

09.00-09.45 Registration

09.45-10.15 Welcome greetings
Alexey Tomilin (Russia)

Session: “Regulation of autophagy in cancer”

Chair: Gerry Melino

10.15-11.00 Plenary lecture
Boris Zhivotovsky, Invited Speaker (Sweden-Russia):
Cross-talk between apoptosis and autophagy:
the role of suppressed translation

11.00-11.30
Gian Maria Fimia, Invited Speaker (Italy):
Role of Ambra1 in the regulation of autophagy in
Oropharyngeal Squamous Cell Carcinoma

11.30-12.00 Coffee Break

Session: “Cancer”

Chair: Amedeo Columbano

12.00-12.30
Gerry Melino, Invited Speaker (Italy):
p53 family regulates metabolism and contributes to the
hypoxic stress response by regulating translation

12.30-12.45
Vladimir Lazarev, (Russia):
The role of GAPDH in cancer cells resistance to hypoxia

12.45-13.00
Qiagen (Sponsor’s presentation)

13.00-13.30
Gennaro Ciliberto, Invited Speaker (Italy):
MiRNAs as key regulators of drug resistance in metastatic melanoma

13.30-14.30 Lunch

Session: “Cancer therapy”

Chair: Gennaro Ciliberto

14.30-15.00
Peter Chumakov, Invited Speaker (Russia):
Panels of oncolytic viruses for the treatment of malignant diseases

15.00-15.30
Amedeo Columbano, Invited Speaker (Italy):
Thyroid hormone administration interferes with HCC progression through
induction of differentiation and metabolic reprogramming

15.30-16.00
Guillermo Velasco, Invited Speaker (Spain):
Stimulation of autophagy-mediated cancer cell
death as a strategy to fight gliomas

16.00-16.30 Coffee Break

Session: “p53 in Cancer”

Chair: Nick Barlev

16.30-17.00
Ivano Amelio, Invited Speaker (United Kingdom):
The Gain and the Loss function in the p53 business

17.00-17.30
Anna Brichkina, Invited Speaker (Germany):
Targeting tumor-associated macrophages for lung cancer therapy

Short talks

17.30-17.45
Bulatov Emil (Russia):
Restoring impaired functions of mutant tumor suppressor p53 using synthetic modulators

17.45-18.00
Kudryavtseva Anna (Russia):
Molecular genetics of paragangliomas

18.00-18.15
Shuvalov Oleg (Russia):
MDM2 ubiquitin-ligase down-regulates energy metabolism of human tumor cell models

18.15-18.30
Lomert Ekaterina (Russia):
Increased level of NF-kappaB affects proliferation and migration rates in lung cancer cells H1299

18.30-20.00 Poster session and drinks

    October 12th

    Session: “Cancer therapy”

    Chair: Guillermo Velasco

    09.30-10.00
    Alessandro Desideri, Invited Speaker (Italy):
    A DNA nanostructure platform for drug delivery,
    miRNA sequestering and cancer proteostasis

    10.00-10.30
    Hans-Uwe Simon, Invited Speaker (Switzerland):
    ATG12 deficiency leads to tumor cell oncosis owing to
    diminished mitochondrial biogenesis and reduced cellular bioenergetics

    10.30-11.00
    Inna Lavrik, Invited Speaker (Germany):
    Delineating death receptor network via rational design of chemical probes

    11.00-11.30
    Coffee Break

    11.30-12.00
    Maxim Nikitin, Invited Speaker (Russia):
    Smart Nanomaterials as Advanced Sensors and Targeted Drug Delivery Agents

    12.00-12.30
    Oleg Demidov (Russia-France):
    Chemotherapy as a modifier of tumor microenvironment

    12.30-13.00
    Evgeny Imyanitov, Invited Speaker (Russia):
    Mechanisms of tumor drug resistance

    13.00-14.00
    Lunch

    Session: “Proteostasis and Transglutaminase type 2”

    Chair: Boris Zhivotovsky

    14.00-14.30
    Said El Alaoui, Invited Speaker (France):
    Tissue Transglutaminase as an emerging target therapy in cancer

    14.30-15.00
    Mauro Piacentini, Invited Speaker (Italy):
    Role of Transglutaminase type 2 in the regulation of proteostasis

    15.00-15.30
    Irina Guzhova, Invited Speaker (Russia):
    Inhibitors of molecular chaperones in anti-cancer therapeutics

    Short Talks

    15.30-15.45
    Tezcan Gulcin (Russia):
    Pyroptosis: A New Theraupeutic Approach for Glioblastoma Therapy

    15.45-16.00
    Kochetkova Elena (Russia):
    Autophagy impairment in Ki-Ras-mutated cancer cells through targeting the lysosomes results in cell death

    16.00-16.15
    Fedorova Olga (Russia):
    MDM2-Mediated Resistance of Lung Cancer Cell Lines to Genotoxic Drugs

    16.15-16.30
    Daks Alexandra (Russia):
    Methyltransferase Set7/9 as a biomarker and potential target for therapy of lung and breast carcinomas

    16.30-16.45
    Shevchenko Konstantin (Russia):
    MIL-100 coated nanoparticles as a potential tool for in vitro delivery of therapeutic agents

    16.45-17.00
    Shevtsov Maxim (Russia):
    Membrane-bound heat shock protein Hsp70 as a theranostic target for cancer therapy

    17.00-17.15
    Bychkov Maxim, (Russia):
    Mambalgin-2 selectively inhibits proliferation of ASIC1a-expressing cancer cells

    17.15-17.25
    Presentation from sponsors
    Luminex

    17.25-17.35
    Concluding remarks
    Nick Barlev and Mauro Piacentini

START TYPING AND PRESS ENTER TO SEARCH