Dear Colleagues!

We would like to invite you to participate in the international conference “Molecular Mechanisms of Autophagy in Diseases” (MMAD) to be held on October 30-31, 2020 in Saint-Petersburg. Autophagy is a ubiquitous and evolutionarily conserved process in eukaryotes that ensures targeted degradation of cytosolic components in the lysosome. It plays an important role in maintaining cellular homeostasis, especially under stress conditions. Autophagy is tied to stress responses through a number of critical signaling pathways, and is orchestrated by a series of core autophagy proteins (ATG proteins). Recent discoveries have revealed the great therapeutic potential of modulating autophagy in a variety of human diseases, including cancer, cardiovascular and neurodegenerative diseases. To emphasize the importance of this biological process is the fact that in 2016, Dr Yoshinori Ohsumi was awarded with the Nobel prize for the discovery of autophagy. The aim of this Conference is to integrate diverse perspectives on the function of autophagy from the fields of genetics, cell biology, oncology, infection and immunity, metabolism, neurodegeneration and drug discovery. We believe that this online meeting will promote an exchange of ideas between young and established scientists, clinicians and industry, to foster the growth of translational autophagy research.

On March 11, WHO declared the COVID-19 pandemic. Extraordinary measures had been taken all around the world to contain virus spread. We realize that changes are not temporal, but more of a permanent character, and we need to adapt our life as researchers to these changing conditions. In light of the current situation, the organizing committee has decided to conduct the conference in the on-line format. We have contacted the prominent invited speakers and they all supported the idea of holding the conference in this format.

The program, abstracts and photo materials of the symposium will be published on the web site (Program, Photogallery). Selected abstracts will be published in “Cell Death Discovery” journal (IF=4,3 Q2; indexed in WoS Core Collection). Presentations and records will be made available for all registered participants of MMAD.

The Early bird registration fee for the conference is prolonged until September, 31, 2020. The full price registration is opened until October 30th. To register on-line, please, visit the page: http://cancerproteostasis.com/registration/online-registration/

The deadline for submission of abstracts is October 15th, 2020. For details and instructions of abstract submission, please, visit the page: http://cancerproteostasis.com/abstract-submission/

We sincerely hope for your understanding and cooperation and look forward to see you at MMAD on October 30-31, 2020!

The Organizing committee of MMAD

Organizers: Mauro Piacentini and Nick Barlev