“Molecular Mechanisms of Autophagy in Diseases”
October 30-31, 2020 Saint Petersburg (Russia)
(Moscow time UTC +3)

OCTOBER 30, FRIDAY

11.00 Welcome by the Chairs

Session 1: Autophagosomes biogenesis
Chair Mauro Piacentini

11.15-11.40 Sharon Tooze (London, United Kingdom) Identification of ULK substrates
11.40-12.05 Tassula Proikas-Cezanne (Tubingen, Germany) Regulation of WIPI function in autophagy
12.05-12.30 Nicholas Ktistakis (Cambridge, UK) The plasticity of the autophagic pathway: making autophagosomes big and small
12.30-12.55 Joern Dengjel (Fribourg, Switzerland) The ULK1-regulated phosphatase network

LUNCH BREAK

Session 2: Selective autophagy 
Chair: Boris Zhivotovsky

14.15-14.40 Patrizia Agostinis (Leuwen, Belgium) Autophagy regulation of lymphangiogenesis
14.40-15.05 Michelangelo Campanella (London, UK) A role for the Nucleus-Associated Mitochondria in Autophagy
15.05-15.30 Anne Simonsen (Oslo, Norway) Regulation of PRKN-independent Mitophagy by Lipid-binding kinases
15.30-15.55 Kevin Ryan (Glasgow, United Kingdom) Autophagy and Atg protein in cancer progression

COFFEE BREAK

Session 3: Autophagy and Cancer 
Chair: Kevin Ryan

16.15-16.40 Gerry Melino, (Rome, Italy) Molecular Mechanisms and Function of the p53 Protein Family Member – p73
16.40-17.05 Boris Zhivotovsky (Moscow, Russia) Apoptosis-Autophagy link: The role of p62 and caspase-2
17.05-17.30 Vojo Deretic (Albuquerque, USA) MERiT, a membrane repair, removal, and replacement system
17.30-17.45 Alhasan Bashar (Russia) ULK-1 dependent autophagy mediates the elimination of defective pluripotent stem cells through upregulation of p53 protein
17.45-18.00 Irina Neganova (Saint-Petersburg, Russia) The role of autophagy in overcoming cellular senescence of human MSCs in 2D-3D-2D model

OCTOBER 31, SATURDAY

Session 4: Autophagy and immune response
Chair: Nick Barlev

10.30-10.55 Guido Kroemer (Paris, France) An extracellular autophagy checkpoint
10.55-11.20 Carmine Settembre (Naples, Italy) Transcriptional regulation of ER-phagy in health and disease
11.20-11.45 Patricia Boya (Madrid, Spain) Autophagy as a cytoprotective response in neurons during aging and disease

COFFEE BREAK

Session 5: Autophagy and Cell Stress
Chair: Guido Kroemer

12.00-12.25 Gian Maria Fimia (Rome, Italy) Role of Ambra1 in the regulation of autophagy in Oropharyngeal Squamous Cell Carcinoma
12.25-12.50 Christian Munz (Zurich, Switzerland) Oxidation in regulation of phagocytosis by autophagy proteins
12.50-13.15 Laurence Zitvogel (Paris, France) The gut microbiome secrets for cancer immunotherapy
13.15-13.30 Olga Fedorova (Saint-Petersburg, Russia) TG2-indicing autophagy in response to DNA damage
13.30-13.45 Alexandra Daks (Saint-Petersburg, Russia) Set7/9 controls the balance between apoptosis and autophagy under genotoxic stress

Brief Conclusion from Nick Barlev

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